Health Technology Assessment a multidisciplinary process that summarises information about the medical, social, economic, and ethical issues related to the use of a health technology in a systematic, transparent, unbiased, and robust manner. Health Technology Assessment differs in its governance, data and evidence requirements, assessment methods, and operational arrangements across different settings and contexts. This course is aimed at introducing the key principles of Health Technology Assessment, its operational modalities, the different models of value assessment and how they link to decision-making.